My Detox Experience – Part 3 – Objective changes

They are here, they are plain, they are numbers… And they are finally coming…!!! The physiological markers, the health parameters… All the geeky part of the experiment that will hopefully shed some “scientific” light on the adaptations of the body to a sudden and rather significant diet change. In this section, I will discuss the most relevant findings, in addition to publishing some of the raw (yep, even numbers can be used raw…!) data on myself (not on the other people in order to respect their privacy).


As you can see from my PRE-detox numbers, if there was a reason I wanted to try the detox diet, it was to see whether I would feel “refreshed” or “energised”, or what it would feel to be “detoxified” (I evetually ended up doing it as part of a group activity and an experiment on myself, but that is another issue…). I was not aiming at losing weight nor body fat, and in fact, I was more concerned about not losing fat free mass than anything else. Starting at 70.77 Kg (by 1.75 m tall, giving a BMI of 23.1 Kg/m2 for those who believe in it…), I ended at 67.46 Kg (BMI 22.03 Kg/m2), with a total loss of 3.31 Kg (or 4.68% of my starting weight). Considering that total body weight is a very poor marker of health or fitness (as is the BMI, on which so many guidelines are based…) my next question was: where did this weight come from? If the numbers don’t lie, 1.14 Kg were fat-free mass, while 2.14 were body fat.

Anthropometric data PRE vs POST
Anthropometric data PRE vs POST

Before celebratory parties get started, I would like to make a couple of considerations:

  • I said if, for the simple reason that at such low level, minimal changes in the machine reading (the so-called reliability of the measuring device), would show as major changes in percentage points. Did my body fat really went from 9% to 6.8%? If I am sure I lost weight (I felt it, I could see it and the scale is much more “reliable” than the BodPod), I can think that most of it was fat, but certainty would need much more data (if it was ever to achieve…). And even then, was it a good thing? With minimum body fat recommended to stay above 5% in elite male athletes, I would leave the answer to you…
  • As mentioned previously, I was not aiming at losing weight or body fat, but rather at maintaining fat free mass while feeling the benefits (if any…) of a plant-based, raw, juiced dietary regime. My fat-free mass went from 64.42 Kg (91%) to 63.25 (93.8%). Maintaining the same consideration as above, this was an unwelcome adaptation, that will lead me to the next part of my data analysis about energy deficit.

For those out there who love playing with numbers, we can indeed see that to lose over 3 Kg in such a short time, a few things need to happen. First and foremost, you must be kept in quite a significant energy deficit (more of that in a moment). This was somehow a pleasant surprise for my brain… I was not just a wimp (if you read Part 2 of my detox experience you will understand), my body was actually paying a rather heavy bill, on a daily basis… Secondly, considering that the mathematical idea of 2.14 Kg of fat equaling 19,260 Cal would give a daily energy deficit of 3,852 Cal (even ignoring the other 1.13 Kg of fat-free mass, a rather unlikely occurrence), my glycogen stores were likely to have been depleted carrying water away with them (pure speculation on this point, if you can suggest any other explanation, I would love to read it in the comment box…). Another pleasant surprise for my brain: my legs and arms were feeling so heavy for a reason!

On another note, I did indeed question the validity of the nutritional information I was given, and would surely recommend the Detox Delight nutritionists to double check their data. So, I lost weight… But how did the rest of my body adapt?


This was a big one indeed…! If there is one test I would recommend to anyone interested in looking at their cardiovascular disease risk (CVD, essentially the risk you have of suffering from a heart attack or similar, the number one causes of death in the Western World), it would be the LPP. Without going too much into details (I might in future posts, but if you cannot wait I would strongly recommend Dr Peter Attia’s blog) the LPP measures not only the classic total cholesterol, HDL-cholesterol (HDL-C), TG and LDL-cholesterol (LDL-C), but it also measures LDL particle number (LDL-P), LDL subclasses, HDL2b, insulin, high sensitive CRP (the most accurate marker of inflammation) and it gives you a Metabolic Syndrome risk score (what you should essentially be concerned about).

Considering the attention I pay to my diet and the amount of physical activity I undertake, I did not expect any major surprise here. And indeed my Metabolic Syndrome risk score started from 0…! And not just that, my HDL-C (the so called “good cholesterol”) was very high with an LDL-C (the “bad boy”) defined as “above optimal”. First sign that my usual lifestyle already works…

Unfortunately though, you might notice a flashy red number next to my LDL-IV particle number… If initially that was a surprise and a concern (recent studies have shown a much higher atherogenic risk of LDL-IV and LDL-III over the bigger LDL-I and LDL-II), it also sparked an almost insatiable hunger for more knowledge and understanding of this part of lipidology. Hours and hours of reading and discussing with other practitioners later, this ultimately let me understand the even higher importance of LDL-P (the actual number of LDL particles, rather than their size) over LDL-subclasses, and even more so, the importance of “concordance” between LDL-C (in my case low) and LDL-P (also low). In this situation, essentially, the mere size of my LDL was irrelevant, as there were so few of them, carrying so little cholesterol, that everything else did not matter…

I would strongly suggest you to refer to other websites and blogs here or from my links page (The Eating Academy or DocsOpinion to just mention a couple of the most useful in my opinion and in my personal journey to understanding these not so widely addressed topics) if you want to know more. It would be not just out of the scope of this page, but surely it would be way far from my competence and knowledge at this stage.


If I defined the LPP test as the one not to miss to measure your CVD risk, the Organix was supposed to be one not to miss to see the effects of the detox diet… If indeed changes in blood lipids and aminoacids might take some time to happen and be recorded, the Organix Profile measures a number of metabolic markers that can be affected by shorter dietary interventions. Not only this, it also measures markers for a number of situations relevant to the so called “functional medicine”, that discipline that deals with sub-clinical insufficiencies or higher concentrations of molecules and minerals that could potentially represent non-optimal health (as much as we know about it at least) or lead to clinical conditions if left untreated. I would like here to stress this point: I am now discussing about biomarkers used in functional medicine, a very different area from the more common concepts of medicine where abnormal indicators are almost invariably associated with a clinical condition or at least prompt some intervention. These biomarkers per se mean hardly anything. More than in other scientific fields, a clinical connection between these markers and clinical symptoms have to be made before considering an intervention. After this short intro, these were my findings, before and after my detox diet:


Wow, I thought after seeing this…! I don’t think there is much to explain when a rapid look at the summary shows such a marked change from various abnormal findings to an almost perfect sheet of “no abnormality found”… If as I explained in the previous paragraph, I and the consulting functional medicine practitioner were not concerned by the PRE findings anyway (I did not present any symptom that would require additional investigations or treatment anyway, as for example if I had sleeping issues associated with my high neurotransmitter metabolism markers), the “normalization” of almost all markers was still a pleasant surprise.

In particular, if the detox diet was meant to help my body somewhere, I should have expected to see some changes in the oxidative stress and detoxification processes… And guess what? My liver seemed to fully reap the benefits of the diet indeed…! My corrected levels of p-hydroxyphenillactate possibly meant a reduced cellular oxidative damage, while the improved detoxification indicators showed that my liver was now working under less pressure.

If until now the effects of the detox diet was just marginally showing some positives, the Organix profile test, surely tilted the balance towards its likely effectiveness, at least into doing what the name suggests: help the body detoxification system…

My Detox Experience – Part 2 – Personal Feelings

I will admit, as you might have felt from Part 1, I was a bit skeptical about trying the juice-only detox diet. The main concern most people coming from a mixed Zone/Paleo nutritional lifestyle (generally promoting a diet with a higher than recommended protein intakes) would have, is related to the amount and quality of proteins available in juiced fruits, veggies and nuts… Fats were also a concern, being fruits and vegetables notoriously almost fat-free (although the nuts part was encouraging). Additionally, training an average of 12-15 hours a week, my estimated total daily caloric expenditure ranges between 3400 and 4000 Cal. Would 8 juices be enough to maintain my energy level and avoid losing lean body mass? Starting at a 9% body fat percentage, I did not even want to lose body fat.

For these reasons and to ensure the whole group would be in safe hands, I requested Claudia and Nicole to provide me with the nutritional information about the plan. While initially surprised about the request, as their approach is not based on calories or macronutrient / micronutrient quantification (their words), Claudia got back to me shortly after with information coming from their HQ in Germany. It came as a spreadsheet containing the nutritional information (only macronutrients and calories) about the 9 juices (even if not fully detailed, at least the main information were there).

My total counts showed that daily caloric intake would have been 2650 Cal, coming from 101g of fats (34.3%), 374g of carbohydrates (56.5%) and 61g of proteins (9.2%). Saturated fats would be 18 of the 101g of fats, sugars would made up 317 of the 374g of carbohydrates, with 37g of fibers.

After crunching the numbers, I was partially reassured about the reasonable caloric intake (albeit in theory insufficient for my daily needs) and a good intake of fats and fibers, while on the other hand the high amount of sugars (not added sugars, none of these nasties in Claudia an Nicole’s kitchen, but still very high) and the low protein profile (which however was still within the recommended 0.8g/Kg/day, although of questionable “quality”), were reasons for concern, not sufficient though to stop me from entering the program.

On the morning of the first day we had all our tests done, before officially drinking our first “Good Morning” bottle. It was no real struggle to get through the first day, although I did not like not being able to refuel after the first workout of the day with a rich meal as my usual. In addition, drinking bottles 4 & 7 proved highly challenging… Believe me, the “chlorophyll water” (wheatgrass and filtered water) is a real nasty… I challenge anyone to say the contrary, unless you’re a cow, or a goat, that is… The main “physiological” difference from any other normal day was the frequency of my visits to the loo…!


The second day went also fairly smooth, although again, training after only one drink for breakfast left me somehow unsatisfied… And similarly not refuelling the way I am used to was also more mentally frustrating than anything else… The intensity of training was still high but the feeling of fatigue was surely more noticeable than usual. Drink 4 & 7 still faced with some hesitation, but then again, if it was all nice and easy, everyone would do it, right? By the end of the day, we also had the first dropout in the group. 6 of us now left to diet…

On the third day I started to see and feel more obvious adaptations… The first one was the heaviness of my legs in the morning. Standing up from bed felt like my 200th deep squat… After managing the get moving and having my morning juice, I felt no need to empty my bowel, a very rare occurrence in my mornings (getting too personal? 🙂 ). After getting to the gym, 2 friends admitted to have had breakfast, as they could not cope with hunger anymore. I personally didn’t feel that hungry, my main feeling was tiredness and heaviness in the legs. I adapted the workout, focusing on my upper body and somehow managed to lift my usual weights. Not being able to join friends for dinner was probably the most annoying aspect of my third dieting day (aside from drink 4 & 7 as you surely know by now!).

The fourth day resembled the third, with increasing tiredness and weakness, now affecting my arms as well. My bowel was still in sleeping mode. I had to force myself into training (at this stage I should have sensibly taken a day off, but I didn’t want to change my initial plans of training as usual) and at a lower than usual intensity, I still managed my 20min interval training followed by 25min circuit session and 15min core workout. While I started to get used to the daily litre of chlorophyll water (humans have amazing adapting skills I realized!), my mood was surely being affected, with my patience being at historical lows and me being highly irritable. I tried an easy indoor tennis match (yes, I’m crazy about physical training, any form, style and shape) I just found myself shouting and screaming like hell at any ball I would not reach, but at the same time my legs were just two heavy bricks to move on court… I’ll admit, I was not enjoying the detox program (I’d better say, it was now really getting to my nerves), but it was one day left only, so I would not give up. I also discussed my feeling with Claudia and Nicole (who very professionally and informally kept following our progress) who offered us a little surprise treat to help us getting through… Despite this, I was stronger than one more of our friends, who gave in to a normal dinner. 7 starting, 3 standing…


No changes in the 5th day. Claudia and Nicole had been very supportive throughout the week, they even sent some extra nibbles (which I decided not to take, the program was clear, only juiced food…), their help and interest in our reaction to the program surely deserving great credit. My bowel still on holiday, my legs still heavy but not enough to stop me from completing a training session in the morning and the training routine I did on the day before the start of the program in the evening: a 3.5km run, followed by a 22min clubbell session. My running time was surprisingly comparable to my usual and so was my heart rate. I felt like it was all a mind game… And that made me happy…

I woke up on day 6 with the only thought of getting my blood sampled and my body analysed as soon as possible, in order to finally have some eggs and chicken for breakfast… Interestingly, while my pre diet urine collection measured around 400ml (overnight), the post detox passed the 600ml mark… Probably my bladder was doing my bowel job too (no news there, I think a personal best not to get anything from there for four consecutive days)… Despite not being seriously hungry during the 5 days, I had always that feel of “I wouldn’t mind having a bite” and I was by now really craving savoury, umami tasting food… By 9.30am I was done, and by 10am breakfast in front of me…! It really was a joy to restart eating… Training was now an unpleasant experience, despite the normal breakfast. But at least I could not only eat pre-workout, I could finally use the much acclaimed early post-exercise window to replenish my body… A strong mental satisfaction for almost anyone involved with fitness…


The day went with a single training session and a celebratory dinner at an Italian restaurant (Carnevale, by Jumeirah Beach Hotel, highly recommended!) with my girlfriend. For a food lover like me, not sitting down for a meal for five days proved more challenging than I expected… And eating good food now felt even more pleasant than before…

With Nicole and Claudia consistently supportive and informative, their question now was if I was experiencing the energy boost the program was supposed to give me… I could not say I felt great, but surely, I could say I was restarting to feel better…

It was indeed by day 7 that I can say things were back to normal. My bowel eventually woke up, getting off bed was effortless and I so wanted (and managed) to nail a great workout… Was it an energy boost? Or just returning to normal levels? I honestly cannot say, but it did feel good!

Returning to my usual life and routine (cooking daily, making time for meals the real Italian way, training hard and eating harder and managing more than a couple of hours before having to run to the toilet) was a real good feel… Surely one of the many things I leant from the experience is how hard it is to change habits, even if for a relatively short period…!

And what are my other personal thoughts about my 5-day Active Detox program? It was an as great introspective experience as an unenjoyably physical one… I discovered even more the importance I give to food… From planning the meal, to buying the ingredients, to cooking and eating… I felt I was stripped of one of my great passions, while in return I was enjoying an incredible amount of spare time… During which, unfortunately, I was too tired to do much anyway… Also missing out on a couple of nights out was not fun. Feeling tired and weak and resisting the temptation of opening the fridge was not easy, by a good test of my commitment. The help and support from Claudia and Nicole was impressive. They managed to satisfy any request about delivery time, alternative juices, even sending us the special treat when they felt our struggles…

To sum up my personal thoughts (still not knowing about the objective changes), I can surely say that it was an interesting and more difficult than expected experience. If it wasn’t for the initial commitment and curiosity to see any objective marker changes, I might have given up on day 4, mainly for the unreasonable thought that I was “wasting away”, losing hardly gained muscle mass due to insufficient energy intake and reduced training intensity… (I know it does not make so much sense in just a 5-day period, but I’m telling you, controlling the human mind is no easy task…!). On the other hand I found very positive the personal reflections about my priorities, considering the likely excessive importance I give to my routine diet and my pre and post workout eating habits (science is mainly with me on the importance of energy, macronutrient, fluids and minerals replacement around exercise, but not so conclusively to justify the extent of my frustration).

Would I recommend it? I’m not sure just yet… Let me see what changed in my body and I’ll let you know…! One thing I would at least suggest, to both potential dieters and Claudia and Nicole, is to try to personalize a bit more the approach, as without being too extreme about nutrient intakes, the “one-diet-fits-all” approach seems to limiting to say the least (especially in an “active” population, which might span from triathletes training endurance in excess of 25hrs a week, to body builders lifting several times their body weight, to recreational fit passionates and anything in between..).

Curious to know more? Did I gain weight? Or lose it? Was it fat? Muscle mass? Did my cardiovascular health change? My metabolism? There is so much more to discover, I strongly recommend you stay tuned for the upcoming posts…!

My Detox Experience – Part 1 – Introduction

Here it is, the drop that made me start my personal blog. My 5-day “detox” juice-only diet. I will start by clarifying that I have no personal interest in any of the companies or tools mentioned in this post. The only reason I will put links, names and comments is to give you a better understanding of the process and if you are interested, to get more information about the topics.


A detox diet is often defined as a nutrition plan lasting a limited amount of time (it varies between a few days and a few weeks), during which most providers will claim that you “flush your system from toxins” or “detoxify your body” from the toxins normally ingested with your diet, or by smoking, etc… In other instances, you will be promised to “alkalize” your system, starting from the principle that too much “acidity” in your system is deleterious and today’s environment will most likely cause your body to be acid. To my knowledge, none of these claims is scientifically proven. However, talk to anyone in a detox plan and you are likely to hear one of these effects… Depending on the company (there is indeed no standard on the program, or on the final objective, apart being “detoxified”) you will be told to avoid certain foods (most commonly animal products and alcohol) and you will only be allowed to eat certain others (usually plant-based only, sometimes only in juiced form, some other times salads are included), often only in their raw form. [Future blog posts will discuss the reasons behind all these restrictions and the potential benefits of raw food (from a scientific point of view)]. The chapter of nuts would also deserve a full dissertation on its own [and it will soon be discussed], as in some programs they are totally banned, while in others they are the major source of proteins and fats, although they will probably be soaked or somehow treated before eating [you will learn why in one of my future posts, just stay tuned].

Detox Delight Middle East is the Dubai franchise of a company headquartered in Germany. In brief, they offer several “detox programs” in which they deliver food to your door at regular intervals for a certain period, so that you do not have to do anything more than just read the information provided and eat what they serve. No shopping, no cooking and no cleaning is required. One of their (very valid) selling point, is indeed their convenience. The foods and drinks come in an ice-box and are freshly made in their own local kitchen, using organically grown and locally sourced products (in Dubai their main provider is Greenheart Organic Farms). Normally the products will have a shelf life of two to three days, so that you have enough food before the next delivery. They offer plant-based raw food only and depending on their programs, they might offer a juice-only package or include salads and snacks. Out of their deliveries you are recommended to only drink water and herbal teas (which they also provide), while you should abstain from any other food, alcohol, caffeine and smoking. Detox Delight Middle East is run by two incredibly passionate women, Claudia and Nicole. They will make sure everything works smoothly and you have all the support you need to make a change (often a big one) in you diet.

Active Detox
Active Detox


Following the positive results achieved by some of our friends with one of the detox program offered by Detox Delight ME (weight loss, improved general wellbeing), I and six other physically active friends decided to try the Active Detox program. It involves having a juice-based only diet of 8 x 500ml juices (mixed fruits, vegetables and nuts) for 5 days. On top of that we also received a daily 250ml bottle of nut milk to take after training.

Before fully throwing ourselves into the program, we agreed to make it in a more “scientific” way. Through Diagnostika Laboratories in Dubai we had the Spectracell Lipoprotein Particles Test and the Metametrix Organix Comprehensive ProfileAmino Acid Profile and Plasma Fatty Acids Profile tests done, in addition to measuring our body height, weight and body composition, using the Cosmed BodPod. All these tests and measurements were taken on the day we started our detox program and then repeated the morning after the end of it, in order to see whether the detox would show any changes in any of the parameters observed. The main parameters to look for were related to cardiovascular risk factors, including blood insulin and inflammatory markers (Lipoprotein Particles), macronutrients metabolism (Organix Profile), plasma pool of amino acids (Amino Acids Profile) and fatty acids (Fatty Acids Profile) and body composition (mainly weight and body fat %, via the BodPod, recognized as one of the most accurate measuring tool by the scientific literature). In a less scientific approach, I also decided to run my regular distance and perform a set workout the night before the start, and then repeat it on the last night of the program, to see whether my performance, personal feel or heart rate would be affected. We agreed not to change our training routine during the program (despite it is recommended to “take it easy” during the detox) as we love training and changing other parameters would have added confounding variables to our results.

Wanna know about the results of our experiment and my personal feedback and review of all parties involved?  I will divide them into personal feelings (what I felt, energy, cravings, good and bad feels, etc..), training and performance changes (HR, running times, fatigue, weight sessions results, etc…), objective health parameters modifications (bloods, urine and body composition) and final review and comments… So, for now… Stay tuned, there is plenty to come…!

My Blog


Hello and welcome! It has taken me a long time to decide whether or not I would like to become a blogger…  I decided to give it a go and see what happens… The tipping point? My latest hands-on experiment on myself… I wanted to share with you the feelings, body changes and performance changes of following a 5-day “detox diet”, consisting of liquid plant-based raw foods only…

I will keep the posts as scientifically sound as possible as one of the gaps I often see in blogs is the lack of scientific approach when making claims about this new product, that training regime of the latest fad diet or food supplement. These are indeed my passions: science, fitness, sports, health, nutrition and cooking and most of not all you will find here is somehow related to one these topics…

With the hope that you will find my posts interesting, I am looking forward to reading your comments…!